Opportunity Information: Apply for PAR 16 404
The NLM Express Research Grants in Biomedical Informatics (R01) opportunity (Funding Opportunity Number PAR-16-404) is a National Institutes of Health grant program run through the National Library of Medicine (NLM) to fund innovative, interdisciplinary research in biomedical informatics and data science. The central purpose is to support the development of new methods, tools, and approaches in biomedical computing and information science, especially when those innovations can be applied to real problems across health and biomedicine. NLM frames biomedical informatics as the science of representing, organizing, managing, integrating, and presenting information related to human health and biology so that it can be learned from, shared, and used effectively. In practical terms, this means the program is interested in projects that improve how biomedical data and knowledge are structured and handled, how different data sources are combined, and how information is delivered to people or systems that need it for decision-making, discovery, and improved outcomes.
The research scope is intentionally broad and includes a wide range of application areas. Examples of domains specifically highlighted include health care delivery, basic biomedical research, clinical and translational research, precision medicine, public health, biosurveillance, and health information management in disasters, along with similar settings where data and information challenges are central. Because of that breadth, the opportunity can fit projects focused on things like novel data integration strategies, improved knowledge representation, advanced analytics or data science methods tailored to biomedical data, and systems that make complex biomedical information more usable in clinical, research, or population health environments. The unifying theme is that the work should be clearly grounded in informatics and data science innovation, not simply the use of existing tools.
Administratively, this is a discretionary grant opportunity using the R01 funding mechanism, categorized under education and health, with CFDA number 93.879. The source information lists an award ceiling of $250,000. The opportunity was created on August 15, 2016, and the listed original closing date is August 8, 2018, which signals that the provided record reflects a specific posted cycle and prospective applicants should confirm whether the program is reissued or updated under a current notice before planning submission.
Eligibility is expansive and includes many types of U.S. and non-U.S. organizations. Eligible applicants include state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; other Native American tribal organizations (including those other than federally recognized tribal governments); public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding institutions of higher education in those categories); for-profit organizations other than small businesses; and small businesses. The announcement also explicitly calls out additional eligible applicant groups such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), faith-based or community-based organizations, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Indian/Native American tribal governments other than federally recognized, non-domestic (non-U.S.) entities (foreign organizations), regional organizations, Tribally Controlled Colleges and Universities (TCCUs), eligible federal agencies, and U.S. territories or possessions. This broad eligibility aligns with the interdisciplinary nature of biomedical informatics and the potential for meaningful contributions from academic, clinical, public sector, community, and industry environments.Apply for PAR 16 404
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "NLM Express Research Grants in Biomedical Informatics (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.879.
- This funding opportunity was created on 2016-08-15.
- Applicants must submit their applications by 2018-08-08. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $250,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs) - NLM Express Research Grants in Biomedical Informatics (R01)
What is this grant opportunity?
This is the NLM Express Research Grants in Biomedical Informatics (R01) funding opportunity, run through the National Library of Medicine (NLM) as part of the National Institutes of Health (NIH). The Funding Opportunity Number is PAR-16-404.
What is the main purpose of PAR-16-404?
The central purpose is to fund innovative, interdisciplinary research in biomedical informatics and data science, particularly work that develops new methods, tools, or approaches in biomedical computing and information science that can be applied to real problems in health and biomedicine.
What does NLM mean by "biomedical informatics" in this program?
NLM frames biomedical informatics as the science of representing, organizing, managing, integrating, and presenting information related to human health and biology so it can be learned from, shared, and used effectively.
What types of projects are a good fit for this opportunity?
Projects are a good fit when they are clearly grounded in informatics and data science innovation and aim to improve how biomedical data and knowledge are structured, combined, managed, or delivered to support decision-making, discovery, and improved outcomes.
Does the program support applied work, or only basic research?
The scope is broad and emphasizes innovations that can be applied to real problems across health and biomedicine. The description highlights practical impact through better data handling, integration, and information delivery.
What kinds of research areas or domains are explicitly mentioned?
Examples of highlighted domains include health care delivery, basic biomedical research, clinical and translational research, precision medicine, public health, biosurveillance, and health information management in disasters, as well as similar settings where data and information challenges are central.
Are data integration projects relevant under this opportunity?
Yes. The opportunity explicitly points to work such as novel data integration strategies and improved ways of combining different data sources.
Are knowledge representation projects relevant under this opportunity?
Yes. Improved knowledge representation is called out as an example area, consistent with the program's interest in how biomedical data and knowledge are structured and handled.
Does the opportunity support analytics or data science methods?
Yes. The scope includes advanced analytics or data science methods tailored to biomedical data, as long as the work is focused on informatics and data science innovation.
Is it enough to use existing tools on biomedical data?
No. The unifying theme is innovation in informatics and data science. The opportunity is not aimed at projects that simply apply existing tools without developing new methods, tools, or approaches.
What funding mechanism is used?
The opportunity uses the NIH R01 funding mechanism.
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is PAR-16-404.
Which NIH institute or center runs this opportunity?
The opportunity is run through the National Library of Medicine (NLM).
What is the CFDA number listed for this opportunity?
The CFDA number listed is 93.879.
What is the award ceiling listed in the source information?
The source information lists an award ceiling of $250,000.
When was this opportunity created?
The opportunity was created on August 15, 2016.
What is the original closing date shown in the record?
The listed original closing date is August 8, 2018.
Does the closing date mean the opportunity is no longer available?
The record reflects a specific posted cycle with an original closing date of August 8, 2018. Prospective applicants should confirm whether the program has been reissued or updated under a current notice before planning a submission.
What type of grant is this described as administratively?
It is described as a discretionary grant opportunity using the R01 mechanism.
What general categories is this opportunity listed under?
It is categorized under education and health.
Who is eligible to apply?
Eligibility is expansive and includes many types of U.S. and non-U.S. organizations, including government entities, academic institutions, nonprofits, for-profits, small businesses, tribal entities, and other specified organizations.
Are U.S. state and local governments eligible?
Yes. Eligible applicants include state governments and local governments such as county, city, or township governments, as well as special district governments.
Are public and private colleges and universities eligible?
Yes. Eligible applicants include public and state-controlled institutions of higher education and private institutions of higher education.
Are independent school districts eligible to apply?
Yes. Independent school districts are listed as eligible applicants.
Are nonprofits eligible?
Yes. Nonprofits with or without 501(c)(3) status are listed as eligible applicants (excluding institutions of higher education within those nonprofit categories, as stated in the eligibility list).
Are for-profit organizations eligible?
Yes. For-profit organizations other than small businesses are listed as eligible, and small businesses are also listed as eligible.
Are federally recognized tribal governments eligible?
Yes. Federally recognized Native American tribal governments are listed as eligible applicants.
Are tribal organizations that are not federally recognized eligible?
Yes. Other Native American tribal organizations (including those other than federally recognized tribal governments) are listed, and the announcement also calls out Indian/Native American tribal governments other than federally recognized.
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions are explicitly called out as eligible.
Are foreign (non-U.S.) organizations eligible?
Yes. Non-domestic (non-U.S.) entities (foreign organizations) are explicitly listed as eligible.
Are eligible federal agencies able to apply?
Yes. Eligible federal agencies are explicitly called out among eligible applicant groups.
Are public housing authorities eligible?
Yes. Public housing authorities/Indian housing authorities are listed as eligible applicants.
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are explicitly called out as additional eligible applicant groups.
Are minority-serving institutions included in the eligibility list?
Yes. The announcement explicitly calls out eligibility for multiple categories of minority-serving institutions, including HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian Serving Institutions, AANAPISIs, TCCUs, and Tribally Controlled Colleges and Universities.
What is the common theme across the wide range of supported domains?
The unifying theme is informatics and data science innovation, especially improvements in representation, organization, management, integration, and presentation of biomedical information so it can be used effectively for discovery, decision-making, and outcomes.
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 16 404) also looked into and applied for these:
| Funding Opportunity |
|---|
| NCI Outstanding Investigator Award (R35) Apply for PAR 16 411 Funding Number: PAR 16 411 Agency: National Institutes of Health Category: Education, Health Funding Amount: $600,000 |
| Core Clinical Centers for the Blood and Marrow Transplant Clinical Trials Network (UG1) Apply for RFA HL 17 018 Funding Number: RFA HL 17 018 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Limited Competition: Data Coordinating Center for the Blood and Marrow Transplant Clinical Trials Network (U24) Apply for RFA HL 17 019 Funding Number: RFA HL 17 019 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NCI Small Grants Program for Cancer Research (NCI Omnibus R03) Apply for PAR 16 416 Funding Number: PAR 16 416 Agency: National Institutes of Health Category: Education, Health Funding Amount: $50,000 |
| NLM Grants for Scholarly Works in Biomedicine and Health (G13) Apply for PAR 16 417 Funding Number: PAR 16 417 Agency: National Institutes of Health Category: Education, Health Funding Amount: $50,000 |
| NLM Information Resource Grants to Reduce Health Disparities (G08) Apply for RFA LM 17 002 Funding Number: RFA LM 17 002 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| "High" or "Medium" Priority AIDS Research on Non-AIDS-defining or AIDS-defining Cancers (R21) Apply for PA 16 425 Funding Number: PA 16 425 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| "High" or "Medium" Priority AIDS Research on Non-AIDS-defining or AIDS-defining Cancers (R01) Apply for PA 16 426 Funding Number: PA 16 426 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Coordinating Center for the HIV/AIDS and Substance Use Cohorts Program (U24) Apply for RFA DA 17 019 Funding Number: RFA DA 17 019 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Grand Opportunity in Medications Development for Substance-Use Disorders (U01) Apply for PAR 16 431 Funding Number: PAR 16 431 Agency: National Institutes of Health Category: Education, Health Funding Amount: $5,000,000 |
| Strategic Alliances for Medications Development to Treat Substance Use Disorders (R01) Apply for PAR 16 430 Funding Number: PAR 16 430 Agency: National Institutes of Health Category: Education, Health Funding Amount: $3,000,000 |
| Health Promotion Among Racial and Ethnic Minority Males (R21) Apply for PA 16 432 Funding Number: PA 16 432 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Symptom Management in HIV-Infected Individuals with Comorbid Conditions (R01) Apply for PA 16 427 Funding Number: PA 16 427 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Symptom Management in HIV-Infected Individuals with Comorbid Conditions (R21) Apply for PA 16 429 Funding Number: PA 16 429 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Encouraging Appropriate Care Using Behavioral Economics through Electronic Health Records (R21/R33) Apply for RFA AG 17 013 Funding Number: RFA AG 17 013 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Drug Abuse Dissertation Research (R36) Apply for PA 16 443 Funding Number: PA 16 443 Agency: National Institutes of Health Category: Education, Health Funding Amount: $50,000 |
| Improving the HIV Pre-Exposure Prophylaxis (PrEP) Cascade (R34) Apply for RFA MH 17 361 Funding Number: RFA MH 17 361 Agency: National Institutes of Health Category: Education, Health Funding Amount: $225,000 |
| Improving the HIV Pre-Exposure Prophylaxis (PrEP) Cascade (R01) Apply for RFA MH 17 360 Funding Number: RFA MH 17 360 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Multi-Site Pilot and Feasibility Studies for System-Level Implementation of Substance Use Prevention and Treatment Services (R34) Apply for PAR 16 456 Funding Number: PAR 16 456 Agency: National Institutes of Health Category: Education, Health Funding Amount: $225,000 |
| Multi-Site Studies for System-Level Implementation of Substance Use Prevention and Treatment Services (R01) Apply for PAR 16 455 Funding Number: PAR 16 455 Agency: National Institutes of Health Category: Education, Health Funding Amount: $500,000 |
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