Opportunity Information: Apply for RFA NS 17 012

This National Institutes of Health (NIH) grant opportunity, titled "Detecting Cognitive Impairment, Including Dementia, in Primary Care and Other Everyday Clinical Settings for the General Public and in Health Disparities Populations (UG3/UH3)," is focused on a practical public health problem: many people with early cognitive impairment or dementia are not identified in everyday medical care until the condition is more advanced. The goal is to fund research projects that create and test real-world clinical approaches for spotting cognitive impairment in large, diverse groups of patients who are seen in primary care settings across the United States. A key point is that the screening or detection process is meant to happen when there is a concern raised by the patient, a family member, or a care provider, rather than as broad, universal screening of everyone regardless of symptoms or concern.

The program emphasizes solutions that actually fit into the pace and workflow of primary care. Applicants are expected to propose clinical paradigms that rely on tools that are simple, standardized, and quick to administer, ideally taking five minutes or less. In plain terms, NIH is looking for approaches that a busy clinic could realistically use without requiring specialized staff, long testing sessions, or complicated equipment. The underlying idea is that if detection tools are too time-consuming or complex, they will not be adopted widely, and the gap in early identification will remain.

A major theme of the announcement is inclusion and equity. The NIH explicitly calls for approaches that work well not only in the general public but also in health disparities populations, meaning groups that experience unequal burdens of disease or unequal access to high-quality care. This can include communities facing barriers related to income, geography, race and ethnicity, language, education, disability, or systemic inequities in healthcare. The intent is to push the field toward detection methods that are valid and useful across many populations, rather than tools that perform well only in narrow or highly resourced clinical environments.

The grant uses a cooperative agreement mechanism and a phased UG3/UH3 structure. In NIH programs, this kind of structure typically supports an initial, milestone-driven planning or early implementation phase (UG3) followed by a later phase (UH3) that supports expanded testing or broader clinical evaluation, assuming early milestones are met. A cooperative agreement also generally means there is substantial involvement from NIH staff during the project, such as coordination, oversight, and collaboration around milestones and progress, rather than a hands-off model.

Eligibility is broad and is designed to allow many types of organizations to participate. Eligible applicants include different levels of government (state, county, city or township, and special districts), independent school districts, public and state-controlled colleges and universities, private institutions of higher education, and a range of nonprofit organizations (both 501(c)(3) and non-501(c)(3)). For-profit organizations (other than small businesses) and small businesses are also eligible. The announcement also highlights additional eligible applicants such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, and tribal governments or organizations including those that are not federally recognized. U.S. territories or possessions can also apply. However, the opportunity draws clear boundaries around foreign involvement: non-U.S. institutions cannot apply as the primary applicant, and non-U.S. components of U.S. organizations are not eligible to apply. At the same time, "foreign components" as defined by NIH policy are allowed, which generally means limited international collaboration can be included when justified, even though the main applicant organization must be based in the United States.

Administrative details in the source information show this is a discretionary funding opportunity from NIH, listed under funding opportunity number RFA-NS-17-012 and categorized under health-related research activities. The CFDA numbers associated with it are 93.853 and 93.866. The original closing date listed is May 9, 2017, and the expected number of awards is four. The award ceiling is not specified in the provided data, which usually means applicants would need to consult the full FOA text for budget expectations, allowable costs, and any project period limits.

Overall, the opportunity is about developing and validating detection approaches that are realistic for primary care and everyday clinical settings, with a strong emphasis on simplicity, standardization, speed, and effectiveness in diverse and underserved populations. The broader public-facing takeaway is that NIH aimed to support projects that could make earlier recognition of cognitive impairment more routine in typical healthcare settings, which can open the door to earlier evaluation, better planning, support services, and more appropriate medical management for patients and families.

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Detecting Cognitive Impairment, Including Dementia, in Primary Care and Other Everyday Clinical Settings for the General Public and in Health Disparities Populations (UG3/UH3)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853, 93.866.
  • This funding opportunity was created on 2017-03-07.
  • Applicants must submit their applications by 2017-05-09. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 4 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
Apply for RFA NS 17 012

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Frequently Asked Questions (FAQs)

What is the title of this NIH grant opportunity?

The opportunity is titled "Detecting Cognitive Impairment, Including Dementia, in Primary Care and Other Everyday Clinical Settings for the General Public and in Health Disparities Populations (UG3/UH3)."

What problem is the grant trying to address?

It targets a practical public health gap: many people with early cognitive impairment or dementia are not identified during routine, everyday medical care until the condition is more advanced.

What is the main goal of the funded projects?

The main goal is to support research projects that create and test real-world clinical approaches to detect cognitive impairment in large, diverse groups of patients seen in primary care settings across the United States.

Is this funding for universal screening of everyone in primary care?

No. The detection process is intended to occur when there is a concern raised by the patient, a family member, or a care provider, rather than broad, universal screening of everyone regardless of symptoms or concern.

Where are the detection approaches expected to be used?

The approaches are intended for primary care and other everyday clinical settings, with an emphasis on routine, real-world environments rather than highly specialized research clinics.

What does NIH mean by approaches that "fit into the pace and workflow" of primary care?

NIH is looking for methods that are realistic for busy clinics to use. The expectation is that the detection approach should not require specialized staff, long testing sessions, or complicated equipment that would slow normal clinic operations.

How long should the proposed tools take to administer?

The program emphasizes tools that are simple, standardized, and quick to administer, ideally taking five minutes or less.

What kinds of tools or processes does NIH want applicants to use?

Applicants are expected to propose clinical paradigms that rely on tools that are simple, standardized, and fast. The underlying idea is that overly time-consuming or complex tools are less likely to be adopted widely in typical clinical care.

Why is there a strong emphasis on simplicity and speed?

The opportunity is framed around real-world adoption: if detection tools are too complex or take too long, they are unlikely to be used in everyday primary care, and early identification gaps will persist.

What populations does NIH want these approaches to work for?

The opportunity emphasizes inclusion and equity. NIH is calling for approaches that work well in the general public and also in health disparities populations.

What are "health disparities populations" in the context of this opportunity?

Health disparities populations are groups that experience unequal burdens of disease or unequal access to high-quality care. The announcement notes barriers that may relate to income, geography, race and ethnicity, language, education, disability, or systemic inequities in healthcare.

What is the intended impact of improving detection in diverse and underserved populations?

The intent is to move the field toward detection methods that are valid and useful across many populations, not only in narrow or highly resourced clinical environments.

What funding mechanism is being used?

This opportunity uses a cooperative agreement mechanism and a phased UG3/UH3 structure.

What does the UG3/UH3 phased structure mean at a high level?

It typically supports an initial milestone-driven phase (UG3) focused on planning or early implementation, followed by a later phase (UH3) supporting expanded testing or broader clinical evaluation, assuming early milestones are met.

What does it mean that this is a "cooperative agreement"?

A cooperative agreement generally means substantial involvement from NIH staff during the project, such as coordination, oversight, and collaboration around milestones and progress, rather than a fully hands-off approach.

Who is eligible to apply?

Eligibility is broad. Eligible applicants include various levels of government (state, county, city or township, and special districts), independent school districts, public and state-controlled colleges and universities, private institutions of higher education, and a range of nonprofit organizations (both 501(c)(3) and non-501(c)(3)). For-profit organizations (other than small businesses) and small businesses are also eligible.

Are tribal governments and tribal organizations eligible?

Yes. The opportunity highlights tribal governments or organizations, including those that are not federally recognized, among eligible applicants.

Are U.S. territories or possessions eligible to apply?

Yes. U.S. territories or possessions can apply.

Are community-based or faith-based organizations eligible?

Yes. The announcement highlights faith-based or community-based organizations as eligible applicants.

Are minority-serving institutions explicitly included as eligible applicants?

Yes. The opportunity highlights Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and related categories.

Can a non-U.S. institution apply as the primary applicant?

No. Non-U.S. institutions cannot apply as the primary applicant for this opportunity.

Can a non-U.S. component of a U.S. organization apply?

No. Non-U.S. components of U.S. organizations are not eligible to apply.

Are any international collaborations allowed?

Yes, "foreign components" as defined by NIH policy are allowed. This generally means limited international collaboration can be included when justified, even though the main applicant organization must be based in the United States.

What is the funding opportunity number (FOA number)?

The funding opportunity number is RFA-NS-17-012.

What type of funding opportunity is this listed as?

It is listed as a discretionary funding opportunity from the National Institutes of Health (NIH) under health-related research activities.

What CFDA numbers are associated with this opportunity?

The CFDA numbers listed are 93.853 and 93.866.

What is the application closing date shown in the provided information?

The original closing date listed is May 9, 2017.

How many awards were expected?

The expected number of awards is four.

Is there an award ceiling listed?

No award ceiling is specified in the provided information. That typically means applicants would need to consult the full funding opportunity announcement for budget expectations, allowable costs, and any project period limits.

What is the broader public-facing takeaway from this opportunity?

NIH aimed to support projects that could make earlier recognition of cognitive impairment more routine in typical healthcare settings, which can open the door to earlier evaluation, better planning, support services, and more appropriate medical management for patients and families.

Browse more opportunities from the same agency: National Institutes of Health

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Applicants also applied for:

Applicants who have applied for this opportunity (RFA NS 17 012) also looked into and applied for these:

Funding Opportunity
Limited Competition: Centers of Biomedical Research Excellence (COBRE) Phase III - Transitional Centers (P30) Apply for PAR 17 208

Funding Number: PAR 17 208
Agency: National Institutes of Health
Category: Health
Funding Amount: $750,000
Research Education: Bridges to the Doctorate (R25) Apply for PAR 17 209

Funding Number: PAR 17 209
Agency: National Institutes of Health
Category: Health
Funding Amount: $300,000
Bridges to the Baccalaureate Program (R25) Apply for PAR 17 210

Funding Number: PAR 17 210
Agency: National Institutes of Health
Category: Health
Funding Amount: $300,000
Nutrition and Alcohol-Related Health Outcomes (R01) Apply for PA 17 211

Funding Number: PA 17 211
Agency: National Institutes of Health
Category: Health
Funding Amount: Case Dependent
Nutrition and Alcohol-Related Health Outcomes (R03) Apply for PA 17 212

Funding Number: PA 17 212
Agency: National Institutes of Health
Category: Health
Funding Amount: $50,000
Nutrition and Alcohol-Related Health Outcomes (R21) Apply for PA 17 213

Funding Number: PA 17 213
Agency: National Institutes of Health
Category: Health
Funding Amount: $200,000
Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Mind and Body Interventions (Collaborative UG3/UH3) Apply for PAR 17 175

Funding Number: PAR 17 175
Agency: National Institutes of Health
Category: Health
Funding Amount: Case Dependent
Mind and Body Intervention Multi-Site Clinical Trial Data Coordinating Center (U24) Apply for PAR 17 173

Funding Number: PAR 17 173
Agency: National Institutes of Health
Category: Health
Funding Amount: Case Dependent
NCCIH Natural Product Phase II Clinical Trial Cooperative Agreement (U01) Apply for PAR 17 216

Funding Number: PAR 17 216
Agency: National Institutes of Health
Category: Health
Funding Amount: Case Dependent
Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Natural Products (Collaborative UG3/UH3) Apply for PAR 17 174

Funding Number: PAR 17 174
Agency: National Institutes of Health
Category: Health
Funding Amount: Case Dependent
Natural Product Multi-Site Clinical Trial Data Coordinating Center (Collaborative U24) Apply for PAR 17 172

Funding Number: PAR 17 172
Agency: National Institutes of Health
Category: Health
Funding Amount: Case Dependent
Limited Competition: Analysis of Data from NIA's Alzheimer's Disease Sequencing Project Follow-Up Study (U01) Apply for PAR 17 214

Funding Number: PAR 17 214
Agency: National Institutes of Health
Category: Health
Funding Amount: Case Dependent
NCCIH Mind and Body Clinical Trial Cooperative Agreement (U01) Apply for PAR 17 215

Funding Number: PAR 17 215
Agency: National Institutes of Health
Category: Health
Funding Amount: Case Dependent
Tobacco Centers of Regulatory Science for Research Relevant to the Family Smoking Prevention and Tobacco Control Act (U54) Apply for RFA OD 17 003

Funding Number: RFA OD 17 003
Agency: National Institutes of Health
Category: Health
Funding Amount: $4,000,000
Enhancing Science, Technology, EnginEering, and Math Educational Diversity (ESTEEMED) Research Education Experiences (R25) Apply for PAR 17 221

Funding Number: PAR 17 221
Agency: National Institutes of Health
Category: Health
Funding Amount: Case Dependent
Hearing Health Care for Adults: Improving Access and Affordability (R21) Apply for PA 17 227

Funding Number: PA 17 227
Agency: National Institutes of Health
Category: Health
Funding Amount: $200,000
NIDCR Dental Specialty and PhD Program (DSPP)(K12) Apply for RFA DE 18 003

Funding Number: RFA DE 18 003
Agency: National Institutes of Health
Category: Health
Funding Amount: Case Dependent
Consumer Assessment of Healthcare Providers and Systems V (CAHPS V) (U18) Apply for RFA HS 17 010

Funding Number: RFA HS 17 010
Agency: Agency for Health Care Research and Quality
Category: Health
Funding Amount: Case Dependent
Tobacco Centers of Regulatory Science for Research Relevant to the Family Smoking Prevention and Tobacco Control Act (U54) Apply for RFA OD 17 006

Funding Number: RFA OD 17 006
Agency: National Institutes of Health
Category: Health
Funding Amount: $4,000,000
AHRQ Mentored Clinical Scientist Research Career Development Award (K08) Apply for PA 17 232

Funding Number: PA 17 232
Agency: Agency for Health Care Research and Quality
Category: Health
Funding Amount: Case Dependent

 

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